WO2006038110A3 - Amphiphilic star block copolymers - Google Patents

Amphiphilic star block copolymers Download PDF

Info

Publication number
WO2006038110A3
WO2006038110A3 PCT/IB2005/003023 IB2005003023W WO2006038110A3 WO 2006038110 A3 WO2006038110 A3 WO 2006038110A3 IB 2005003023 W IB2005003023 W IB 2005003023W WO 2006038110 A3 WO2006038110 A3 WO 2006038110A3
Authority
WO
WIPO (PCT)
Prior art keywords
copolymer
block
hydrophobic
block copolymers
star block
Prior art date
Application number
PCT/IB2005/003023
Other languages
French (fr)
Other versions
WO2006038110A8 (en
WO2006038110A2 (en
Inventor
Lahoussine Ouali
Andreas Herrmann
Celine Ternat
Christopher John Georg Plummer
Harm-Anton Klok
Georg Kreutzer
Jan-Anders E Manson
Horst Sommer
Maria Ines Velazco
Original Assignee
Firmenich & Cie
Lahoussine Ouali
Andreas Herrmann
Celine Ternat
Christopher John Georg Plummer
Harm-Anton Klok
Georg Kreutzer
Jan-Anders E Manson
Horst Sommer
Maria Ines Velazco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie, Lahoussine Ouali, Andreas Herrmann, Celine Ternat, Christopher John Georg Plummer, Harm-Anton Klok, Georg Kreutzer, Jan-Anders E Manson, Horst Sommer, Maria Ines Velazco filed Critical Firmenich & Cie
Priority to EP05791696A priority Critical patent/EP1814924A2/en
Priority to BRPI0516259-9A priority patent/BRPI0516259A/en
Priority to JP2007535267A priority patent/JP5090915B2/en
Priority to MX2007004048A priority patent/MX301374B/en
Priority to CN2005800337635A priority patent/CN101035823B/en
Publication of WO2006038110A2 publication Critical patent/WO2006038110A2/en
Publication of WO2006038110A3 publication Critical patent/WO2006038110A3/en
Publication of WO2006038110A8 publication Critical patent/WO2006038110A8/en
Priority to US11/690,074 priority patent/US20070160561A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Abstract

The present invention relates to a basically spherical hyperbranched block copolymer having an internal hydrophobic block and an external hydrophilic block. Within the spherical copolymer, the hydrophobic block constitutes a hydrophobic layer, suitable to associate or encapsulate hydrophobic bioactive agents, while the hydrophilic block provides an outer layer, which is suitable to render the copolymer soluble or dispersible in aqueous solutions. Also claimed is a method for preparing the copolymer, which is suitable to encapsulate fragrances, flavours, drugs, agrochemicals, for example.
PCT/IB2005/003023 2004-10-08 2005-10-10 Amphiphilic star block copolymers WO2006038110A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP05791696A EP1814924A2 (en) 2004-10-08 2005-10-10 Amphiphilic star block copolymers
BRPI0516259-9A BRPI0516259A (en) 2004-10-08 2005-10-10 block copolymer compound, block copolymer, nano-capsule, process for manufacturing block copolymer, use of block copolymer, method for encapsulating and / or associating with at least one lipophilic functional agent, and, fragrant product
JP2007535267A JP5090915B2 (en) 2004-10-08 2005-10-10 Amphiphilic star block polymer
MX2007004048A MX301374B (en) 2004-10-08 2005-10-10 Amphiphilic star block copolymers.
CN2005800337635A CN101035823B (en) 2004-10-08 2005-10-10 Amphiphilic star block copolymers
US11/690,074 US20070160561A1 (en) 2004-10-08 2007-03-22 Amphiphilic star block copolymers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04104955.2 2004-10-08
EP04104955 2004-10-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/690,074 Continuation US20070160561A1 (en) 2004-10-08 2007-03-22 Amphiphilic star block copolymers

Publications (3)

Publication Number Publication Date
WO2006038110A2 WO2006038110A2 (en) 2006-04-13
WO2006038110A3 true WO2006038110A3 (en) 2006-08-17
WO2006038110A8 WO2006038110A8 (en) 2006-09-21

Family

ID=34929682

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/003023 WO2006038110A2 (en) 2004-10-08 2005-10-10 Amphiphilic star block copolymers

Country Status (8)

Country Link
US (1) US20070160561A1 (en)
EP (1) EP1814924A2 (en)
JP (1) JP5090915B2 (en)
CN (1) CN101035823B (en)
BR (1) BRPI0516259A (en)
MX (1) MX301374B (en)
RU (1) RU2007117150A (en)
WO (1) WO2006038110A2 (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007048672A1 (en) * 2005-10-25 2007-05-03 Evonik Degussa Gmbh Preparations containing hyperbranched polymers
DE102005051342A1 (en) * 2005-10-25 2007-04-26 Goldschmidt Gmbh Encapsulation and controlled release of biologically active drugs with enzymatically degradable hyperbranched carrier polymers
DE102006046073A1 (en) * 2006-09-27 2008-04-03 Henkel Kgaa Hyperbranched polymers for hygienic equipment
JP5340956B2 (en) * 2006-12-20 2013-11-13 アーケマ・インコーポレイテッド Encapsulation and / or binding of polymers
EP1982698A1 (en) * 2007-04-18 2008-10-22 Evonik Degussa GmbH Preparations for controlled release of natural bioactive materials
DE102008024868A1 (en) * 2008-05-23 2009-11-26 Merck Patent Gmbh Polymerization process for the production of core-shell particles
DE102008034106A1 (en) * 2008-07-21 2010-01-28 Evonik Röhm Gmbh Block copolymers based on (meth) acrylate with A-P structure
US8815971B2 (en) 2008-12-22 2014-08-26 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8822610B2 (en) 2008-12-22 2014-09-02 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US9783628B2 (en) 2009-04-23 2017-10-10 ATRP Solutions, Inc. Dual-mechanism thickening agents for hydraulic fracturing fluids
US8569421B2 (en) 2009-04-23 2013-10-29 ATRP Solutions, Inc. Star macromolecules for personal and home care
US8173750B2 (en) 2009-04-23 2012-05-08 ATRP Solutions, Inc. Star macromolecules for personal and home care
UA105793C2 (en) * 2009-05-11 2014-06-25 Басф Се Hyperbranched polycarbonates for solubilization of low-solubility active substances
US8013065B2 (en) * 2009-06-09 2011-09-06 International Business Machines Corporation Methods for making multi-branched polymers
KR20120107116A (en) * 2009-12-18 2012-09-28 바스프 에스이 Hyperbranched polyester having a hydrophobic core for solubilizing active ingredients of low solubility
WO2011101757A1 (en) * 2010-02-17 2011-08-25 Firmenich Sa Cyclic oxy compounds as perfuming ingredients
US9186642B2 (en) 2010-04-28 2015-11-17 The Procter & Gamble Company Delivery particle
US9993793B2 (en) 2010-04-28 2018-06-12 The Procter & Gamble Company Delivery particles
US9587064B2 (en) 2010-12-08 2017-03-07 ATRP Solutions, Inc. Salt-tolerant star macromolecules
WO2012116073A2 (en) * 2011-02-23 2012-08-30 The Board Of Trustees Of The University Of Illinois Amphiphilic dendron-coils, micelles thereof and uses
WO2012138690A2 (en) 2011-04-07 2012-10-11 The Procter & Gamble Company Conditioner compositions with increased deposition of polyacrylate microcapsules
CN103458859A (en) 2011-04-07 2013-12-18 宝洁公司 Personal cleansing compositions with increased deposition of polyacrylate microcapsules
CN103458858B (en) 2011-04-07 2016-04-27 宝洁公司 There is the shampoo Compositions of the deposition of the polyacrylate microcapsule of enhancing
US9295734B2 (en) * 2011-06-23 2016-03-29 Shimadzu Corporation Branched amphipathic block polymer and molecular aggregate and drug delivery system using same
US8445577B2 (en) * 2011-07-25 2013-05-21 Iowa State University Research Foundation, Inc. Amphiphilic multi-arm copolymers and nanomaterials derived therefrom
JP6294885B2 (en) 2012-08-30 2018-03-14 エーティーアールピー ソリューションズ インコーポレイテッドＡＴＲＰ Ｓｏｌｕｔｉｏｎｓ，Ｉｎｃ． Star polymer, star polymer composition, and method for producing star polymer
US9623122B2 (en) * 2012-09-04 2017-04-18 Shimadzu Corporation Molecular assembly using branched amphiphilic block polymer, and drug transportation system
CN105263978B (en) 2013-02-04 2018-04-17 Atrp解决方案公司 Salt tolerant star-like macromolecules
CN103214637B (en) * 2013-04-23 2013-12-04 何涛 Hyperbranched polymer nano sustained-release material and preparation method thereof
US9315637B2 (en) * 2013-12-20 2016-04-19 The Regents Of The University Of California Junction-functionalized block copolymers
GB2521655A (en) * 2013-12-27 2015-07-01 Nipsea Technologies Pte Ltd Water dispersible dendritic polymers
MX2017000076A (en) 2014-07-03 2017-05-01 Atrp Solutions Inc Surfactant-compatible star macromolecules.
US10618998B2 (en) * 2014-11-12 2020-04-14 Purdue Research Foundation Poly(alkylene carbonate)-based amphiphilic block copolymers and methods of use thereof
WO2016123107A1 (en) * 2015-01-28 2016-08-04 The Administrators Of The Tulane Educational Fund Nanoparticle polymer grafted dispersants and unimolecular micelles and methods of use
CN104998550B (en) * 2015-06-30 2017-10-10 天津大学 The antipollution milipore filter and preparation method of amphipathic surface modifying material of the filling with crosslinking hydrophobic section
CN108078926B (en) * 2017-12-20 2020-07-07 临沂大学 Tumor active targeting star-shaped amphiphilic polymer micelle nano-drug and preparation method thereof
GB201815523D0 (en) * 2018-09-24 2018-11-07 Imperial Innovations Ltd Polymers
US20230106497A1 (en) * 2020-02-20 2023-04-06 Medtronic, Inc. Drug infusion devices compatible with drug formulations
CN114735943B (en) * 2022-04-12 2023-09-26 江苏大学 Preparation method of poly (3-cyclohexyl allyl propionate) nano brush

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371147A (en) * 1990-10-11 1994-12-06 Permeable Technologies, Inc. Silicone-containing acrylic star polymers, block copolymers and macromonomers
US5399620A (en) * 1991-12-04 1995-03-21 Basf Aktiengesellschaft Block copolymers of acrylate and methacrylate units
US5763548A (en) * 1995-03-31 1998-06-09 Carnegie-Mellon University (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization
US5807937A (en) * 1995-11-15 1998-09-15 Carnegie Mellon University Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties
WO2002026867A2 (en) * 2000-09-29 2002-04-04 The Regents Of The University Of California Dendrimeric support or carrier macromolecule
US6379683B1 (en) * 1999-03-02 2002-04-30 L'oreal Nanocapsules based on dendritic polymers
US20020115798A1 (en) * 2000-12-20 2002-08-22 Sridevi Narayan-Sarathy Star-branched anionic polymers
WO2003000777A2 (en) * 2001-01-19 2003-01-03 Shearwater Corporation Multi-arm block copolymers as drug delivery vehicles
US20030045644A1 (en) * 1999-04-06 2003-03-06 L'oreal Composition comprising polymers having a star structure, the polymers, and their use
US6552146B1 (en) * 1999-04-06 2003-04-22 L'oreal S.A. Composition comprising polymers having a star structure, the polymers, and their use
US20030236354A1 (en) * 2002-04-04 2003-12-25 Kennedy Joseph P. Star block copolymers comprising polyisobutylene-B-polyacrylonitrile arms radiating from an aromatic core
EP1433799A2 (en) * 2002-12-23 2004-06-30 Ucb, S.A. Star shaped acrylic block copolymer
WO2004060977A1 (en) * 2002-12-30 2004-07-22 Nektar Therapeutics Al, Corporation Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3924896C1 (en) 1989-07-27 1990-09-27 Blaupunkt-Werke Gmbh, 3200 Hildesheim, De
WO1992007013A1 (en) * 1990-10-11 1992-04-30 Permeable Technologies, Inc. Novel silicone-containing polymers and oxygen permeable hydrophilic contact lenses therefrom
DE19524045A1 (en) 1995-07-01 1997-01-02 Basf Ag Highly functionalized polyurethanes
JPH10204022A (en) * 1997-01-23 1998-08-04 T Hasegawa Co Ltd Production of 3-cyclohexylpropionic acid
FR2759582A1 (en) * 1997-02-14 1998-08-21 Oreal DEODORANT COMPOSITION
US6569956B1 (en) 1999-12-22 2003-05-27 Basf Corporation Hyperbranched polyol macromolecule, method of making same, and coating composition including same
US20040009229A1 (en) * 2000-01-05 2004-01-15 Unger Evan Charles Stabilized nanoparticle formulations of camptotheca derivatives
AU4830901A (en) 2000-02-09 2001-08-20 Ciba Specialty Chemicals Holding Inc. Hyperbranched amphiphilic polymeric additives and polymer compositions with increased surface energy
JP2002265613A (en) * 2001-03-07 2002-09-18 Kawamura Inst Of Chem Res Star-shaped polymer micelle including porphyrin
US7063895B2 (en) * 2001-08-01 2006-06-20 National Starch And Chemical Investment Holding Corporation Hydrophobically modified solution polymers and their use in surface protecting formulations
WO2003046032A2 (en) * 2001-11-29 2003-06-05 L'oreal Adhesive block ethylene copolymers, cosmetic compositions containing same, and use thereof in cosmetics
DE60229165D1 (en) * 2001-12-13 2008-11-13 Firmenich & Cie COMPOUNDS FOR THE CONTROLLED RELEASE OF ACTIVE MOLECULES
US20060052545A1 (en) * 2002-07-26 2006-03-09 Olvier Guerret Adhesive composition for a humid medium, based on block compolymers comprising at least one hydrophilic block
EP1443058A1 (en) 2003-01-29 2004-08-04 Firmenich Sa Polymeric particles and fragrance delivery systems

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371147A (en) * 1990-10-11 1994-12-06 Permeable Technologies, Inc. Silicone-containing acrylic star polymers, block copolymers and macromonomers
US5399620A (en) * 1991-12-04 1995-03-21 Basf Aktiengesellschaft Block copolymers of acrylate and methacrylate units
US5763548A (en) * 1995-03-31 1998-06-09 Carnegie-Mellon University (Co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization
US6538091B1 (en) * 1995-11-15 2003-03-25 Carnegie Mellon University Atom or group transfer radical polymerization
US5807937A (en) * 1995-11-15 1998-09-15 Carnegie Mellon University Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties
US6379683B1 (en) * 1999-03-02 2002-04-30 L'oreal Nanocapsules based on dendritic polymers
US20030045644A1 (en) * 1999-04-06 2003-03-06 L'oreal Composition comprising polymers having a star structure, the polymers, and their use
US6552146B1 (en) * 1999-04-06 2003-04-22 L'oreal S.A. Composition comprising polymers having a star structure, the polymers, and their use
WO2002026867A2 (en) * 2000-09-29 2002-04-04 The Regents Of The University Of California Dendrimeric support or carrier macromolecule
US20020115798A1 (en) * 2000-12-20 2002-08-22 Sridevi Narayan-Sarathy Star-branched anionic polymers
WO2003000777A2 (en) * 2001-01-19 2003-01-03 Shearwater Corporation Multi-arm block copolymers as drug delivery vehicles
US20040170595A1 (en) * 2001-01-19 2004-09-02 Nektar Therapeutics Al, Corporation Multi-arm block copolymers as drug delivery vehicles
US20030236354A1 (en) * 2002-04-04 2003-12-25 Kennedy Joseph P. Star block copolymers comprising polyisobutylene-B-polyacrylonitrile arms radiating from an aromatic core
EP1433799A2 (en) * 2002-12-23 2004-06-30 Ucb, S.A. Star shaped acrylic block copolymer
WO2004060977A1 (en) * 2002-12-30 2004-07-22 Nektar Therapeutics Al, Corporation Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles

Also Published As

Publication number Publication date
CN101035823B (en) 2012-07-04
MX301374B (en) 2012-07-16
CN101035823A (en) 2007-09-12
EP1814924A2 (en) 2007-08-08
JP2008516041A (en) 2008-05-15
RU2007117150A (en) 2008-11-20
US20070160561A1 (en) 2007-07-12
JP5090915B2 (en) 2012-12-05
WO2006038110A8 (en) 2006-09-21
MX2007004048A (en) 2007-05-24
BRPI0516259A (en) 2008-08-26
WO2006038110A2 (en) 2006-04-13

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